HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxy-4-(methylamino)-5-nitrobenzoic acid → 5-Amino-2-methoxy-4-(methylamino)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxy-4-(methylamino)-5-nitrobenzoic acid | HCID 10987937 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 5-Amino-2-methoxy-4-(methylamino)benzoic acid | HCID 59529838 | — |
Reaction Steps
Prepared analogously to example 1b by hydrogenation of 2-methoxy-4-methylamino-5-nitro-benzoic acid using palladium/charcoal 10% in THF and methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08916599B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-39fe1257e009453385f81700c9e7a2f6 |
| Source note | uspto-grants-2014_12 |