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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1406469Generated: October 30, 2026

Thionyl Chloride → 4-Amino-5-nitro-2-fluoro-benzoyl chloride

https://huagongshe.com/reaction/1406469

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant4-Amino-2-fluoro-5-nitrobenzoic acidHCID 59785337—
Solvent1,2-DichloroethaneHCID 11—
Product4-Amino-5-nitro-2-fluoro-benzoyl chlorideHCID 8666038099%

Reaction Steps

Prepared analogously to example 53a from 4-amino-5-nitro-2-fluoro-benzoic acid and thionyl chloride in 1,2-dichloroethane. Yield: 99%

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08916599B2
Source datasetuspto-grants-2014_12
ORD IDord-fd8f67242e6c4c45aa2ab2824c6df5d0
Source noteuspto-grants-2014_12