HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-bromopyridine → HCID 86660385, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-bromopyridine | HCID 70622 | — |
| Reactant | 3,4-dinitrobenzoyl Chloride | HCID 11806491 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86660385 | HCID 86660385 | — |
Reaction Steps
A mixture 3,4-dinitro-benzoyl chloride (1.78 g, 7.8 mmol) and 5-bromo-2-amino-pyridine (1.35 g, 7.8 mmol) in 20 mL DMF was stirred overnight. After evaporation of the solvent, the residue was purified by chromatography on silica gel (eluent gradient: dichloromethane/methanol 100:0->75:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08916599B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-8ffaf219205f493ba70c90ecccccc823 |
| Source note | uspto-grants-2014_12 |