HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylcarbodiimide → Ethyl 2-(2,6-dichlorophenylamino)-6-fluoro-1-methyl-1H-benzimidazole-5-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylcarbodiimide | HCID 12734 | — |
| Reactant | Ethyl 5-(3-(2,6-dichlorophenyl)thioureido)-2-fluoro-4-(methylamino)benzoate | HCID 86660379 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | Ethyl 2-(2,6-dichlorophenylamino)-6-fluoro-1-methyl-1H-benzimidazole-5-carboxylate | HCID 67229860 | — |
Reaction Steps
Prepared analogously to example 127e from ethyl 5-(3-(2,6-dichlorophenyl)thioureido)-2-fluoro-4-(methylamino)benzoate and DIC in acetonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08916599B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-0f6ec26b6da34efa9b80886da70c6887 |
| Source note | uspto-grants-2014_12 |