HCID 67231343, compound → HCID 67230443, compound

HRID 1406536Notes

Reaction equation

HRID 1406536 reaction equation
[NH2:1][C:2]1[C:10]([N+:11]([O-])=O)=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([O:14][CH2:15][C:16]([F:19])([F:18])[F:17])[CH:3]=1>[Pd].CO>[NH2:1][C:2]1[C:10]([NH2:11])=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[C:4]([O:14][CH2:15][C:16]([F:17])([F:18])[F:19])[CH:3]=1

Participants

4

Reactant 1

HCID 67231343HCID 67231343, compound

Product 1

HCID 67230443HCID 67230443, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

Prepared analogously to example 1b from the product obtained from 582d by hydrogenation with palladium on charcoal in methanol.

Workup

  1. customPrepared analogously to example 1b from the product

Sources & evidence

ORD record
ord-5f977257e01f454ab863545464ce592f
Source dataset
uspto-grants-2014_12
Patent number
US08916599B2

Reaction notes

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