HCID 67230020, compound → HCID 86660397, compound

HRID 1406539Notes

Reaction equation

HRID 1406539 reaction equation
[CH2:1]([O:3][C:4](=[O:19])[C:5]1[CH:10]=[C:9]([NH2:11])[C:8]([NH2:12])=[CH:7][C:6]=1[O:13][CH2:14][C:15]([F:18])([F:17])[F:16])[CH3:2].[Cl:20][C:21]1[C:26]([Cl:27])=[CH:25][CH:24]=[C:23]([F:28])[C:22]=1[N:29]=[C:30]=[S:31]>C(#N)C>[NH2:12][C:8]1[C:9]([NH:11][C:30]([NH:29][C:22]2[C:23]([F:28])=[CH:24][CH:25]=[C:26]([Cl:27])[C:21]=2[Cl:20])=[S:31])=[CH:10][C:5]([C:4]([O:3][CH2:1][CH3:2])=[O:19])=[C:6]([O:13][CH2:14][C:15]([F:16])([F:18])[F:17])[CH:7]=1

Participants

4

Reactant 2

HCID 67230020HCID 67230020, compoundHCID 83409909HCID 83409909, compound

Product 1

HCID 86660397HCID 86660397, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Prepared analogously to example 583h from ethyl-4,5-diamino-2-(2,2,2-trifluoro-ethoxy)-benzoate (synthesis described at example 575) and 2,3-dichloro-6-fluoro-1-isothiocyanato-benzene in acetonitrile.

Sources & evidence

ORD record
ord-5ea15ad397364560b27df15a1bffcc72
Source dataset
uspto-grants-2014_12
Patent number
US08916599B2

Reaction notes

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