Ethyl 4-amino-2-ethoxy-5-nitro-benzoate → Ethyl 4,5-diamino-2-ethoxy-benzoate

HRID 1406542Notes

Reaction equation

HRID 1406542 reaction equation
[NH2:1][C:2]1[C:12]([N+:13]([O-])=O)=[CH:11][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[C:4]([O:16][CH2:17][CH3:18])[CH:3]=1>[Pd].C(O)C>[NH2:1][C:2]1[C:12]([NH2:13])=[CH:11][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[C:4]([O:16][CH2:17][CH3:18])[CH:3]=1

Participants

4

Reactant 1

HCID 67230429Ethyl 4-amino-2-ethoxy-5-nitro-benzoate

Product 1

HCID 67229822Ethyl 4,5-diamino-2-ethoxy-benzoate

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Prepared analogously to example 1b from the product obtained from (599b) by hydrogenation with palladium on charcoal in ethanol.

Workup

  1. customPrepared analogously to example 1b from the product

Sources & evidence

ORD record
ord-c5f3e3b86218426fbce8836c1c229899
Source dataset
uspto-grants-2014_12
Patent number
US08916599B2

Reaction notes

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