Ethyl 4-(3-chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)thiophene-2-carboxylate → 4-(3-Chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)thiophene-2-carboxylic acid
Reaction equation
[Cl:1][c:2]1[cH:3][c:4](-[c:5]2[s:6][c:7]([C:8]([OH:9])=[O:10])[cH:11][c:12]2-[c:13]2[cH:14][cH:15][cH:16][c:17]([C:18]#[N:19])[cH:20]2)[cH:21][c:22]([F:23])[cH:24]1.[Cl:25][c:26]1[cH:27][c:28](-[c:33]2[cH:34][c:35]([C:46](=[O:47])[O:48][CH2:49][CH3:50])[s:36][c:37]2-[c:38]2[cH:39][c:40]([Cl:45])[cH:41][c:42]([F:44])[cH:43]2)[cH:29][cH:30][c:31]1[F:32]>>[Cl:25][c:26]1[cH:27][c:28](-[c:33]2[cH:34][c:35]([C:46](=[O:47])[OH:48])[s:36][c:37]2-[c:38]2[cH:39][c:40]([Cl:45])[cH:41][c:42]([F:44])[cH:43]2)[cH:29][cH:30][c:31]1[F:32]Participants
3
Sources & evidence
- ORD record
- ord-d0dd26f7623d4e359811c4a8510117e9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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