Hydrazine → HCID 86681353, compound

Participants

Reaction Steps

Synthesized according to General Procedure C: 6{15} (4.76 g, 14.4 mmol, 1 equiv.), anhydrous hydrazine (1.4 mL, 43.2 mmol, 3 equiv.), ethanol (28.9 mL). Purification by silica gel column chromatography (4:1 EtOAc:MeOH) afforded 1{15} (3.70 g, 81%) as a white solid. 1H-NMR (500 MHz, CDCl3): δ 8.13 (br s, 1H), 7.55 (d, 2H, J=8.0 Hz), 7.41 (d, 2H, J=8.0 Hz), 3.84 (br s, 2H), 3.53 (s, 2H), 3.07 (s, 2H), 2.53 (br s, 4H), 2.45 (br s, 4H). 13C-NMR (125 MHz, CDCl3): δ 170.3, 142.2, 129.3 (q, JC-F=32.0 Hz), 129.0, 125.1 (q, JC-F=3.8 Hz), 19624.1 (q, JC-F=270.5 Hz) 129.1, 62.2, 60.5, 53.6, 53.0. 19F-NMR (470 MHz, CDCl3): δ-62.8.

Provenance & Evidence