Hydrazine → HCID 86681357, compound

Participants

Reaction Steps

Synthesized according to General Procedure C: 6{17} (5.57 g, 16.1 mmol, 1 equiv.), anhydrous hydrazine (1.5 mL, 48.3 mmol, 3 equiv.), ethanol (32.4 mL). Purification by silica gel column chromatography (4:1 EtOAc:MeOH) afforded 1{17} (4.67 g, 87%) as a beige solid. 1H-NMR (500 MHz, CDCl3): δ 8.15 (br s, 1H), 7.28 (d, 2H, J=8.0 Hz), 7.11 (d, 2H, J=8.0 Hz), 3.83 (br s, 2H), 3.45 (s, 2H), 3.03 (s, 2H), 2.49 (br s, 4H), 2.41 (br s, 4H). 13C-NMR (125 MHz, CDCl3): δ 170.3, 148.1, 136.7, 130.1, 120.5, 120.3 (q, JC-F=255.5 Hz), 61.8, 60.4, 53.5, 52.9. 19F-NMR (470 MHz, CDCl3): −58.3.

Provenance & Evidence