Ethanol → 3-methyl 1-(phenylmethyl) 4-[3-chloro-4-(trifluoromethyl)phenyl]-5,6-dihydro-1,3(2H)-pyridinedicarboxylate
Reaction equation
[C:43](=[O:44])([O-:45])[O-:46].[CH3:49][CH2:50][O:51][CH2:52][CH3:53].[CH3:54][c:55]1[cH:56][cH:57][cH:58][cH:59][cH:60]1.[CH3:61][CH2:62][OH:63].[Cl:29][c:30]1[cH:31][c:32]([B:40]([OH:41])[OH:42])[cH:33][cH:34][c:35]1[C:36]([F:37])([F:38])[F:39].[F:1][C:2]([F:3])([F:4])[S:5]([O:6][CH:7]1[CH:8]([C:23](=[O:24])[O:25][CH3:26])[CH2:9][N:10]([C:13](=[O:14])[O:15][CH2:16][c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[CH2:11][CH2:12]1)(=[O:27])=[O:28].[Na+:47].[Na+:48].[cH:64]1[cH:65][cH:66][c:67]([P:68]([Pd:69]([P:70]([c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)([c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)[c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)([P:89]([c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)([c:96]2[cH:97][cH:98][cH:99][cH:100][cH:101]2)[c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)[P:108]([c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)([c:115]2[cH:116][cH:117][cH:118][cH:119][cH:120]2)[c:121]2[cH:122][cH:123][cH:124][cH:125][cH:126]2)([c:127]2[cH:128][cH:129][cH:130][cH:131][cH:132]2)[c:133]2[cH:134][cH:135][cH:136][cH:137][cH:138]2)[cH:139][cH:140]1>>[C:7]1([c:32]2[cH:31][c:30]([Cl:29])[c:35]([C:36]([F:37])([F:38])[F:39])[cH:34][cH:33]2)=[C:8]([C:23](=[O:24])[O:25][CH3:26])[CH2:9][N:10]([C:13](=[O:14])[O:15][CH2:16][c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[CH2:11][CH2:12]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-ae13816db5a449c3b07358d24c76a3f5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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