Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Fluoroaniline | HCID 9731 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | HCID 89724309 | HCID 89724309 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 89751814 | HCID 89751814 | — |
Reaction Steps
iPr2NEt (0.2 mL) and 4-fluoroaniline (39.2 mg) added into the solution of ethyl 2-((2-((4-((4-((1-(4-chlorophenyl)cyclopropyl)amino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)benzamido)methyl)cyclopentyl)amino)-2-oxoacetate (40 mg) in EtOH (2 mL) and the reaction was stirred at 155° C. for 3 days. The product was isolated by preparative HPLC system.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08916702B2 |
|---|
| Source dataset | uspto-grants-2014_12 |
|---|
| ORD ID | ord-9e8a7d43ce8444759e1b31d6ee04f638 |
|---|
| Source note | uspto-grants-2014_12 |
|---|
