HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoroaniline → HCID 86691675, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoroaniline | HCID 9731 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | HCID 86691676 | HCID 86691676 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86691675 | HCID 86691675 | — |
Reaction Steps
To a solution of 2-(((1-((4-((4-((1-(4-chlorophenyl)cyclopropyl)amino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl)amino)benzamido)methyl)cyclopropyl)methyl)amino)-2-oxoacetic acid (17 mg) and TBTU (10.33 mg) in DMF (2 mL) was added 4-fluoroaniline (3.58 mg). The mixture was stirred at room temperature for 16 hours, before being purified by preparative HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08916702B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-5889df8e1b0d43fa95f108bf58dd3e9c |
| Source note | uspto-grants-2014_12 |