Benzene → 3-(p-Chlorobenzyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane

HRID 140739Notes

Reaction equation

HRID 140739 reaction equation
[CH3:24][O:25][CH2:26][CH2:27][O:28][AlH2-:29][O:30][CH2:31][CH2:32][O:33][CH3:34].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[N:8]2[CH2:9][C:10]3([c:14]4[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]4)[CH2:11][CH:12]3[CH2:13]2)[cH:21][cH:22]1.[Na+:23].[cH:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][N:8]2[CH2:9][C:10]3([c:14]4[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]4)[CH2:11][CH:12]3[CH2:13]2)[cH:21][cH:22]1

Participants

5

Reactant 4

HCID 241BenzeneHCID 923Sodium ionHCID 16721212Bis(2-methoxyethoxy)alumanuideHCID 20468348(4-Chlorophenyl)[1-(4-chlorophenyl)-3-azabicyclo[3.1.0]hexan-3-yl]methanone

Product 1

HCID 132790213-(p-Chlorobenzyl)-1-(p-chlorophenyl)-3-azabicyclo[3.1.0]hexane

Sources & evidence

ORD record
ord-b1920d8868e54dc48d86256cc659877d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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