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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1407541Generated: October 31, 2026

3-Bromophenol → HCID 67356276, compound

https://huagongshe.com/reaction/1407541

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromophenolHCID 11563—
Reactant2,3-Dihydro-1,4-benzodioxin-6-olHCID 9115273—
Reactant1-((5-(Trifluoromethyl)furan-2-yl)methyl)indoline-2,3-dioneHCID 67356488—
ReactantHCID 67357620HCID 67357620—
ProductHCID 67356276HCID 67356276—

Reaction Steps

Following the procedure as described in PREPARATION 2A and making non-critical variations using 2,3-dihydrobenzo[b][1,4]dioxin-6-ol to replace 3-bromophenol, and 4,7-dimethoxy-1-[2-(2-methoxyethoxy)ethyl]-1H-indole-2,3-dione to replace 1-((5-(trifluoromethyl)furan-2-yl)methyl)indoline-2,3-dione, 3-hydroxy-3-(7-hydroxy-2,3-dihydro-1,4-benzodioxin-6-yl)-4,7-dimethoxy-1-[2-(2-methoxyethoxy)ethyl]-1,3-dihydro-2H-indol-2-one was obtained (53%): MS (ES+) m/z 443.9 (M−17).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08916580B2
Source datasetuspto-grants-2014_12
ORD IDord-f62c6f0fae9a4753856778331b339e1c
Source noteuspto-grants-2014_12