Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1408102Generated: November 1, 2026

3-(benzyl(methyl)amino)-N-(2-methoxyethyl)propanamide → N-(2-methoxyethyl)-3-(methylamino)propanamide

https://huagongshe.com/reaction/1408102

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(benzyl(methyl)amino)-N-(2-methoxyethyl)propanamideHCID 66586806—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductN-(2-methoxyethyl)-3-(methylamino)propanamideHCID 4382781128.4%

Reaction Steps

To a solution of 3-(benzyl(methyl)amino)-N-(2-methoxyethyl)propanamide (1.1 g, 4.39 mmol, 1.00 equiv) in methanol (50 mL) was added 5% palladium-on-carbon (50 mg) and the suspension stirred under a hydrogen atmosphere for 2 h. The solids were filtered out and the mixture was concentrated under vacuum to afford 200 mg (28%) of the product as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08916569B2
Source datasetuspto-grants-2014_12
ORD IDord-7cea0043927743c192d12c325b82e44e
Source noteuspto-grants-2014_12