1-Bromo-3,5-difluorobenzene → HCID 2758294, compound

HRID 1408276Notes

Reaction equation

HRID 1408276 reaction equation
Br[C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[C:4]([F:9])[CH:3]=1.[CH3:10][O:11][C:12]1[CH:22]=[CH:21][C:15]([C:16](C(Cl)=O)=[O:17])=[CH:14][CH:13]=1>>[F:9][C:4]1[CH:3]=[C:2]([CH:7]=[C:6]([F:8])[CH:5]=1)[C:16]([C:15]1[CH:21]=[CH:22][C:12]([O:11][CH3:10])=[CH:13][CH:14]=1)=[O:17]

Participants

3

Reactant 2

HCID 1363131-Bromo-3,5-difluorobenzeneHCID 45080940(4-Methoxyphenyl)(oxo)acetyl chloride

Product 1

HCID 2758294HCID 2758294, compound

Procedure

The procedure from Step 1 of Example 1 was followed except that: 1-bromo-3,5-difluorobenzene was used instead of tribromobenzene and 4-methoxybenzoyl carbonyl chloride was used in place of benzoyl chloride to provide a product with mass spectrum corresponding the structure of 3,5-difluoro-4′-methoxybenzophenone.

Sources & evidence

ORD record
ord-951c0fb5c8304d60bfb8c32fc4ab6c9a
Source dataset
uspto-grants-2014_12
Patent number
US08920928B2

Reaction notes

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