Methanol → 1-(4-Hydroxy-4-[4-fluorophenyl]butyl)-3-(3-hydroxyphenyl)piperidine
Reaction equation
[BH4-:26].[CH3:28][OH:29].[Na+:27].[O:1]=[C:2]([CH2:3][CH2:4][CH2:5][N:6]1[CH2:7][CH:8]([c:12]2[cH:13][c:14]([OH:18])[cH:15][cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)[c:19]1[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]1>>[OH:1][CH:2]([CH2:3][CH2:4][CH2:5][N:6]1[CH2:7][CH:8]([c:12]2[cH:13][c:14]([OH:18])[cH:15][cH:16][cH:17]2)[CH2:9][CH2:10][CH2:11]1)[c:19]1[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]1Participants
5
Sources & evidence
- ORD record
- ord-b4e683ac3618463fa5f6eaa4c41828e0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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