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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1408446Generated: November 1, 2026

2-Chloro-4,6-bis(morpholin-4-yl)-1,3,5-triazine → HCID 58507914, compound

https://huagongshe.com/reaction/1408446

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4,6-bis(morpholin-4-yl)-1,3,5-triazineHCID 224967—
Reactant3-Fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridineHCID 16414268—
SolventEthyl acetate hexaneHCID 21226206—
ProductHCID 58507914HCID 5850791431%

Reaction Steps

Following the general procedure A, 4,4′-(6-chloro-1,3,5-triazine-2,4-diyl)dimorpholine was coupled with 3-fluoropyridine-5-boronic acid pinacol ester with reaction time of 15 h. Chromatography (hexane/ethyl acetate 1:1) gave the 31% of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921361B2
Source datasetuspto-grants-2014_12
ORD IDord-d6ca00a9fe3c4e2f9b1d3c9261384151
Source noteuspto-grants-2014_12