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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1408447Generated: October 31, 2026

2-Chloro-4,6-bis(morpholin-4-yl)-1,3,5-triazine → HCID 46202651, compound

https://huagongshe.com/reaction/1408447

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4,6-bis(morpholin-4-yl)-1,3,5-triazineHCID 224967—
Reactant2-Aminopyrimidine-5-boronic acid, pinacol esterHCID 17750212—
SolventEthyl acetate hexaneHCID 21226206—
ProductHCID 46202651HCID 46202651—

Reaction Steps

Following the general procedure A, 4,4′-(6-chloro-1,3,5-triazine-2,4-diyl)dimorpholine was coupled with 2-aminopyrimidine-5-boronic acid pinacol ester with reaction time of 17 h. Chromatography (hexane/ethyl acetate 1:1) gave the title compound as a colorless solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921361B2
Source datasetuspto-grants-2014_12
ORD IDord-be4c686904894f6886759df46314ee77
Source noteuspto-grants-2014_12