Methanol → 3-Amino-N-cyclopropyl-2-hydroxyhexanamide

HRID 140849Notes

Reaction equation

HRID 140849 reaction equation
[CH3:28][OH:29].[CH:1]1([NH:4][C:5]([CH:6]([CH:7]([CH2:8][CH2:9][CH3:10])[N:11]([CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[OH:26])=[O:27])[CH2:2][CH2:3]1.[OH-:30].[OH-:32].[Pd+2:31]>>[CH:1]1([NH:4][C:5]([CH:6]([CH:7]([CH2:8][CH2:9][CH3:10])[NH2:11])[OH:26])=[O:27])[CH2:2][CH2:3]1

Participants

5

Reactant 4

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 69005015HCID 69005015, compound

Product 1

HCID 208049823-Amino-N-cyclopropyl-2-hydroxyhexanamide

Sources & evidence

ORD record
ord-44bf24dafa564a8f95ad596d8c0b7fcd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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