Lawesson's reagent → HCID 58423962, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 6-bromo-2-(3-chlorophenyl)spiro[chroman-4,4′-imidazolidine]-2′,5′-dione (470 mg, 1.16 mmol) and Lawesson's Reagent (468 mg, 1.16 mmol) in 1,4-dioxane (16 mL) was stirred at 110° C. overnight. The solvent was removed in vacuo and the residue was purified by preparative TLC to give 6-bromo-2-(3-chlorophenyl)-2′-thioxospiro[chroman-4,4′-imidazolidin]-5′-one (350 mg, 71%).

Provenance & Evidence