Lawesson's reagent → HCID 58424072, compound

Participants

Reaction Steps

A suspension of 6-bromo-2-methyl-2-phenylspiro[chroman-4,4′-imidazolidine]-2′,5′-dione (1.16 g, 3 mmol) and Lawesson's Reagent (1.21 g, 3 mmol) in dry 1,4-dioxane (24 mL) was refluxed for 24 h. The mixture was concentrated in vacuo and the residue was purified by column to give 6-bromo-2-methyl-2-phenyl-2′-thioxospiro[chroman-4,4′-imidazolidin]-5′-one (748 mg, 61%). 1H-NMR (CDCl3): 1.75 (s, 3H), 3.78 (m, 2H), 5.79 (s, 1H), 6.94 (m, 1H), 7.14 (m, 1H), 7.22 (m, 1H), 7.26-7.53 (m, 5H), 8.39 (s, 1H).

Provenance & Evidence