HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → 3-(4-Iodomethyl-4-isothiocyanato-2-phenyl-chroman-6-yl)-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | Potassium thiocyanate | HCID 516872 | — |
| Reactant | HCID 67174268 | HCID 67174268 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 3-(4-Iodomethyl-4-isothiocyanato-2-phenyl-chroman-6-yl)-benzonitrile | HCID 86657451 | — |
Reaction Steps
To a solution of 3-(4-methylene-2-phenyl-chroman-6-yl)-benzonitrile (50 mg, 0.156 mmol) in CHCl3 (5 mL) was added I2 (93 mg, 0.367 mmol), KSCN (76 mg, 0.78 mmol) and catalyst amount t-BtNBr. The mixture was stirred overnight and used directly.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08921359B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-eda42085e8cd4f2bbcc430b469c089d5 |
| Source note | uspto-grants-2014_12 |