Hydrochloric Acid → HCID 68004038, compound

Participants

Reaction Steps

A solution of 25 (1.70 g, 4.6 mmol) in dichloromethane (10 mL) was stirred with 4 mol/L HCl in dioxane (15 mL) in a closed vessel overnight at room temperature. The resulting suspension was stirred for 1 h with ethyl ether. The solid precipitated was collected by filtration and washed several times with ethyl ether to afford 1.42 g (100%) of 26 as a pale yellow foam (HCl salt). The identity of compound 26 was confirmed by LC/MS and was used directly for the next step. LC/MS (M+1) 310.

Provenance & Evidence