Pentanoic Acid → HCID 178441776, compound

HRID 1409434Notes

Reaction equation

HRID 1409434 reaction equation
[NH:1]1[CH:5]=[C:4]([C:6]([O:8][CH3:9])=[O:7])[N:3]=[CH:2]1.[CH3:10][CH2:11][CH2:12][CH2:13]C(O)=O>>[CH2:10]([C:2]1[NH:1][CH:5]=[C:4]([C:6]([O:8][CH3:9])=[O:7])[N:3]=1)[CH2:11][CH2:12][CH3:13]

Participants

3

Reactant 2

HCID 7991Pentanoic AcidHCID 178418785HCID 178418785, compound

Product 1

HCID 178441776HCID 178441776, compound

Procedure

The title compound was prepared using the procedure described in Example 55(a) starting from methyl 1H-imidazole-4-carboxylate (5 g, 39.7 mmol) and n-valeric acid (13 ml, 119 mmol). Yield: 1.2 g. 1H-NMR (400 MHz; CDCl3): δ 0.92 (t, 3H), 1.24-1.29 (m, 2H), 1.68-1.76 (m, 2H), 2.76 (t, 2H), 3.87 (s, 3H), 7.62 (s, 1H), 9.92 (bs, 1H).

Sources & evidence

ORD record
ord-162573c51c3943a4b0f07d6ba2f1a64b
Source dataset
uspto-grants-2014_12
Patent number
US08921378B2

Reaction notes

Loading…