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HRID1409443

反应详情

EQUATION

反应方程式

HRID 1409443 的结构方程式

REACTANTS

反应物

2
结构：C[C@H](N)Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1
HCID67170882

4-[1-[(2S)-2-Aminopropyl]-1H-pyrazol-3-yl]-2-chlorobenzonitrile

C13H13ClN4

结构：C[Si](C)(C)CCOCn1cc(C(=O)O)nc1C(N)=O
HCID70980297

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@H](Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1cn(COCC[Si](C)(C)C)c(C(N)=O)n1
HCID70984096

未命名化合物

PROCEDURE

实验过程

The title compound was prepared using the procedure described in Example 32(e) starting from 2-carbamoyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole-4-carboxylic acid (400 mg, 1.4 mmol) and (S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile (366 mg, 1.4 mmol). The product was purified with flash-chromatography. Yield 410 mg. LC-MS: [M+1]=528.24.

WORKUP

后处理

  1. customThe product was purified with flash-chromatography