HCID 67169360, compound → HCID 66575739, compound

Participants

Reaction Steps

The title compound was prepared using the procedure described in Example 32(e) starting from 2-(2-hydroxypropan-2-yl)-oxazole-4-carboxylic acid (0.3 g, 1.75 mmol) and (S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-(trifluoromethyl)benzonitrile (0.516 mg, 1.75 mmol). The product was purified by column chromatography. Yield 270 mg. 1H-NMR (400 MHz; DMSO-d6): δ 1.13 (d, 3H), 1.51 (s, 6H), 4.30-4.52 (m, 3H), 5.67 (s, 1H), 7.05 (s, 1H), 7.86 (d, 1H), 8.17 (d, 2H), 8.28 (d, 2H), 8.47 (s, 1H).

Provenance & Evidence