(S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chloro-6-fluorobenzonitrile → HCID 86714679, compound

Participants

Reaction Steps

The title compound was prepared using the procedure described in Example 32(e) starting from 2-(1-ethoxyethyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole-4-carboxylic acid (1.27 mmol, 400 mg) and (S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chloro-6-fluorobenzonitrile (1.27 mmol, 350 mg). The product was purified by flash-chromatography. Yield 230 mg. LC-MS: [M+1]=575.28.

Provenance & Evidence