Toluene → HCID 86714680, compound

Participants

Reaction Conditions

Reaction Steps

Into a flask containing ethyl diazoacetate (52.63 mmol, 6 g) in toluene (100 ml), 3-butyn-2-ol (78.94 mmol, 6.6 g) was added at RT and stirred at 100° C. for 5 h. The solvent was evaporated and the crude was purified by flash-chromatography. Yield 697 mg. 1H-NMR (400 MHz; CDCl3): δ 1.22-1.28 (m, 3H), 1.39 (t, 3H), 2.72-2.78 (m, 1H), 2.82-2.91 (m, 1H), 4.10-4.17 (m, 1H), 4.38 (q, 2H), 6.64 (s, 1H).

Provenance & Evidence