Diethyl Ether → HCID 70981635, compound

Participants

Reaction Steps

The title compound was prepared using the procedure described in Example 2(d) starting from ethyl 5-(2-oxopropyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazole-3-carboxylate (5.24 mmol, 1.7 g) and 3 M solution of MeMgI in ether (6.78 mmol, 2.2 ml). Yield 301 mg. 1H-NMR (400 MHz; CDCl3): δ −0.05 (s, 9H), 0.89 (t, 2H), 1.24 (s, 6H), 1.38 (t, 3H), 2.76 (s, 2H), 3.57 (t, 2H), 4.34 (q, 2H), 5.81 (s, 2H), 6.76 (s, 1H).

Provenance & Evidence