Trifluoroacetic acid → HCID 86689250, compound

Participants

Reaction Steps

The title compound was synthesized by procedures and steps analogous to those described in Example 5 above, but using (S)-7-bromo-3-chloro-1-fluorospiro[chromeno[2,3-c]pyridine-5,3′-pyrrolo[3,4-c]pyridin]-1′-amine (14c-2) in step 3. MS m/z=447.5 [M+H]+. Calculated for C23H12ClF2N5O.C2HF3O2: 561.85 (TFA salt) 1H NMR (400 MHz, MeOH) δ ppm 7.15 (s, 1H) 7.22 (s, 1H) 7.35 (ddd, J=7.14, 5.18, 1.76 Hz, 1H) 7.64 (d, J=8.80 Hz, 1H) 7.78 (d, J=8.61 Hz, 1H) 7.91 (ddd, J=9.88, 7.73, 1.76 Hz, 1H) 8.15 (d, J=4.70 Hz, 1H) 8.22 (d, J=5.09 Hz, 1H) 8.77 (s, 1H) 9.02 (d, J=5.28 Hz, 1H).

Provenance & Evidence