Lithium Hydroxide → HCID 71237636, compound

Participants

Reaction Conditions

Reaction Steps

The product from step B (750 mg, 2.197 mmol) in THF (15 ml) was treated at rt with 1 M aqueous lithium hydroxide (4.83 ml, 4.83 mmol). The mixture was heated at 60° C. for approximately 12 h, then cooled to rt and concentrated. The resulting residue was treated with 2M aq HCl (4.40 mL) and lyophilized twice from water (5 mL) to afford the title compound. HPLC/MS: 328.2 (M+1); Rt=0.95 min (LC-2 HPLC conditions).

Provenance & Evidence