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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1409749Generated: October 25, 2026

2-Chloro-5-(trifluoromethyl)pyrimidine → HCID 71112316, compound

https://huagongshe.com/reaction/1409749

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-(trifluoromethyl)pyrimidineHCID 13317019—
Reactanttert-butyl N-cyclopropyl-N-[(3S,4R)-3-fluoropiperidin-4-yl]carbamateHCID 68290240—
ProductHCID 71112316HCID 71112316—

Reaction Steps

The title compound is prepared from tert-butyl N-cyclopropyl-N-[(3S,4R)-3-fluoropiperidin-4-yl]carbamate and 2-chloro-5-trifluoromethyl-pyrimidine following a procedure analogous to that described for Intermediate 87.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921398B2
Source datasetuspto-grants-2014_12
ORD IDord-55f19808c66842e7ac26abdcb487ed41
Source noteuspto-grants-2014_12