2-(4-Cyanomethyl-phenyl)-pyrimidine-5-carboxylic acid (1-cyano-piperidin-4-yl)-cyclopropyl-amide → 2-(4-Cyanomethyl-phenyl)-pyrimidine-5-carboxylic acid cyclopropyl-[1-(3-phenyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-amide

Participants

Reaction Steps

The title compound is prepared from 2-(4-cyanomethyl-phenyl)-pyrimidine-5-carboxylic acid (1-cyano-piperidin-4-yl)-cyclopropyl-amide and N-hydroxy-benzamidine following a procedure analogous to that described in Example 6. LC (method 3): tR=2.05 min; Mass spectrum (ESI+): m/z=506 [M+H]+.

Provenance & Evidence