2-Chloro-5-ethylpyrimidine → HCID 86686169, compound

HRID 1409762Notes

Reaction equation

HRID 1409762 reaction equation
[CH:1]1([N:4]([CH:19]2[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]2)[C:5]([C:7]2[CH:8]=[N:9][C:10]([N:13]3[CH:17]=[CH:16][N:15]=[C:14]3[CH3:18])=[N:11][CH:12]=2)=[O:6])[CH2:3][CH2:2]1.Cl[C:26]1[N:31]=[CH:30][C:29]([CH2:32][CH3:33])=[CH:28][N:27]=1>>[CH:1]1([N:4]([CH:19]2[CH2:24][CH2:23][N:22]([C:26]3[N:31]=[CH:30][C:29]([CH2:32][CH3:33])=[CH:28][N:27]=3)[CH2:21][CH2:20]2)[C:5]([C:7]2[CH:12]=[N:11][C:10]([N:13]3[CH:17]=[CH:16][N:15]=[C:14]3[CH3:18])=[N:9][CH:8]=2)=[O:6])[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 35727632-Chloro-5-ethylpyrimidineHCID 710937562-(2-Methyl-imidazol-1-yl)-pyrimidine-5-carboxylic acid cyclopropyl-piperidin-4-yl-amide

Product 1

HCID 86686169HCID 86686169, compound

Procedure

The title compound is prepared from 2-(2-methyl-imidazol-1-yl)-pyrimidine-5-carboxylic acid cyclopropyl-piperidin-4-yl-amide and 2-chloro-5-ethylpyrimidine following a procedure analogous to that described in Example 3. LC (method 10): tR=1.39 min; Mass spectrum (ESI+): m/z=433 [M+H]+.

Sources & evidence

ORD record
ord-2bc88e04e1b74877a44d41612d5029fc
Source dataset
uspto-grants-2014_12
Patent number
US08921398B2

Reaction notes

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