6-(1H-IMIDAZOL-1-YL)PYRIDAZINE-3-CARBOXYLIC ACID → HCID 86686172, compound

HRID 1409765Notes

Reaction equation

HRID 1409765 reaction equation
[CH:1]1([NH:4][CH:5]2[CH2:10][CH2:9][N:8]([C:11]3[N:16]=[CH:15][C:14]([CH2:17][CH3:18])=[CH:13][N:12]=3)[CH2:7][CH2:6]2)[CH2:3][CH2:2]1.[N:19]1([C:24]2[N:29]=[N:28][C:27]([C:30](O)=[O:31])=[CH:26][CH:25]=2)[CH:23]=[CH:22][N:21]=[CH:20]1>>[CH:1]1([N:4]([CH:5]2[CH2:10][CH2:9][N:8]([C:11]3[N:12]=[CH:13][C:14]([CH2:17][CH3:18])=[CH:15][N:16]=3)[CH2:7][CH2:6]2)[C:30]([C:27]2[N:28]=[N:29][C:24]([N:19]3[CH:23]=[CH:22][N:21]=[CH:20]3)=[CH:25][CH:26]=2)=[O:31])[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 64163926-(1H-IMIDAZOL-1-YL)PYRIDAZINE-3-CARBOXYLIC ACIDHCID 68289588N-cyclopropyl-1-(5-ethylpyrimidin-2-yl)piperidin-4-amine

Product 1

HCID 86686172HCID 86686172, compound

Procedure

The title compound is prepared from cyclopropyl-[1-(5-ethyl-pyrimidin-2-yl)-piperidin-4-yl]-amine and 6-imidazol-1-yl-pyridazine-3-carboxylic acid following a procedure analogous to that described in Example 1. LC (method 13): tR=2.44 min; Mass spectrum (ESI+): m/z=419 [M+H]+.

Sources & evidence

ORD record
ord-5b81ece698344ecca9cd6d206d9f4d90
Source dataset
uspto-grants-2014_12
Patent number
US08921398B2

Reaction notes

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