[1-(3-Tert-butyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-cyclopropyl-amine → HCID 86686180, compound

HRID 1409775Notes

Reaction equation

HRID 1409775 reaction equation
[C:1]([C:5]1[N:9]=[C:8]([N:10]2[CH2:15][CH2:14][CH:13]([NH:16][CH:17]3[CH2:19][CH2:18]3)[CH2:12][CH2:11]2)[O:7][N:6]=1)([CH3:4])([CH3:3])[CH3:2].[O:20]1[C:24]([C:25]2[N:26]=[CH:27][C:28]([C:31](O)=[O:32])=[N:29][CH:30]=2)=[CH:23][N:22]=[CH:21]1>>[C:1]([C:5]1[N:9]=[C:8]([N:10]2[CH2:11][CH2:12][CH:13]([N:16]([CH:17]3[CH2:19][CH2:18]3)[C:31]([C:28]3[CH:27]=[N:26][C:25]([C:24]4[O:20][CH:21]=[N:22][CH:23]=4)=[CH:30][N:29]=3)=[O:32])[CH2:14][CH2:15]2)[O:7][N:6]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 68289566[1-(3-Tert-butyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-cyclopropyl-amineHCID 86686158HCID 86686158, compound

Product 1

HCID 86686180HCID 86686180, compound

Procedure

The title compound is prepared from [1-(3-tert-butyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-cyclopropyl-amine and 5-oxazol-5-yl-pyrazine-2-carboxylic acid following a procedure analogous to that described in Example 1. LC (method 8): tR=1.57 min; Mass spectrum (ESI+): m/z=438 [M+H]+.

Sources & evidence

ORD record
ord-99825b323b884ad7acbe081e746b466e
Source dataset
uspto-grants-2014_12
Patent number
US08921398B2

Reaction notes

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