HCID 68289599, compound → HCID 86686183, compound

HRID 1409781Notes

Reaction equation

HRID 1409781 reaction equation
[CH:1]1([NH:4][CH:5]2[CH2:10][CH2:9][N:8]([C:11]3[O:15][N:14]=[C:13]([CH2:16][CH2:17][CH3:18])[N:12]=3)[CH2:7][CH2:6]2)[CH2:3][CH2:2]1.[O:19]1[C:23]([C:24]2[N:25]=[CH:26][C:27]([C:30](O)=[O:31])=[N:28][CH:29]=2)=[CH:22][N:21]=[CH:20]1>>[CH:1]1([N:4]([CH:5]2[CH2:10][CH2:9][N:8]([C:11]3[O:15][N:14]=[C:13]([CH2:16][CH2:17][CH3:18])[N:12]=3)[CH2:7][CH2:6]2)[C:30]([C:27]2[CH:26]=[N:25][C:24]([C:23]3[O:19][CH:20]=[N:21][CH:22]=3)=[CH:29][N:28]=2)=[O:31])[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 68289599HCID 68289599, compoundHCID 866861585-Oxazol-5-yl-pyrazine-2-carboxylic acid

Product 1

HCID 86686183HCID 86686183, compound

Procedure

The title compound is prepared from cyclopropyl-[1-(3-propyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-amine and 5-oxazol-5-yl-pyrazine-2-carboxylic acid following a procedure analogous to that described in Example 1. LC (method 8): tR=1.48 min; Mass spectrum (ESI+): m/z=424 [M+H]+.

Sources & evidence

ORD record
ord-a883d5110cd749f49ebb0f4ffdb364f9
Source dataset
uspto-grants-2014_12
Patent number
US08921398B2

Reaction notes

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