HCID 66759906, compound → HCID 86686184, compound

HRID 1409784Notes

Reaction equation

HRID 1409784 reaction equation
[CH:1]1([NH:4][CH:5]2[CH2:10][CH2:9][N:8]([C:11]3[CH:16]=[N:15][C:14]([CH3:17])=[CH:13][N:12]=3)[CH2:7][CH2:6]2)[CH2:3][CH2:2]1.[O:18]1[C:22]([C:23]2[CH:31]=[CH:30][C:26]([C:27](O)=[O:28])=[CH:25][N:24]=2)=[CH:21][N:20]=[CH:19]1>>[CH:1]1([N:4]([CH:5]2[CH2:10][CH2:9][N:8]([C:11]3[CH:16]=[N:15][C:14]([CH3:17])=[CH:13][N:12]=3)[CH2:7][CH2:6]2)[C:27](=[O:28])[C:26]2[CH:30]=[CH:31][C:23]([C:22]3[O:18][CH:19]=[N:20][CH:21]=3)=[N:24][CH:25]=2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 66759906HCID 66759906, compoundHCID 68290086N-cyclopropyl-1-(5-methylpyrazin-2-yl)piperidin-4-amine

Product 1

HCID 86686184HCID 86686184, compound

Procedure

The title compound is prepared from cyclopropyl-[1-(5-methyl-pyrazin-2-yl)-piperidin-4-yl]-amine and 6-oxazol-5-yl-nicotinic acid following a procedure analogous to that described in Example 1. LC (method 7): tR=0.96 min; Mass spectrum (ESI+): m/z=405 [M+H]+.

Sources & evidence

ORD record
ord-8e51d34e36554985bad990a80c5dd6a5
Source dataset
uspto-grants-2014_12
Patent number
US08921398B2

Reaction notes

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