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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1409839Generated: October 30, 2026

ethyl (3R)-piperidine-3-carboxylate → HCID 25211918, compound

https://huagongshe.com/reaction/1409839

Reaction equation

Participants

RoleNameHCIDCharge
Reactantethyl (3R)-piperidine-3-carboxylateHCID 185582—
Reactant5-(4-Methyl-5-trifluoromethyl-isoxazol-3-yl)-thiophene-2-carboxylic acidHCID 25210997—
ProductHCID 25211918HCID 25211918—

Reaction Steps

Prepared from 5-(5-Trifluoromethyl-4-methyl-isoxazol-3-yl)-thiophene-2-carboxylic acid and (R)-(−)-nipecotic acid, ethyl ester (TCI America, Portland Oreg., USA) in the same manner as the R isomer. Colorless solid (220 mg, 70%). LC/MS 6.76 min, [M+1]+ 417.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921399B2
Source datasetuspto-grants-2014_12
ORD IDord-495b81e941254cfb8335e6844e09523e
Source noteuspto-grants-2014_12