HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22795159, compound → HCID 25212206, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22795159 | HCID 22795159 | — |
| Reactant | 5-(4-Methyl-5-trifluoromethyl-isoxazol-3-yl)-thiophene-2-carboxylic acid | HCID 25210997 | — |
| Product | HCID 25212206 | HCID 25212206 | 81% |
Reaction Steps
Prepared from 5-(5-Trifluoromethyl-4-methyl-isoxazol-3-yl)-thiophene-2-carboxylic acid and (3S,4R)-3,4-Piperidinediol (CAS [868051-84-7]) in the same manner as the (3R,4S) isomer (Example 87) to afford product as a colorless solid (303 mg, 81%). LC/MS 5.43 min, [M+1]+ 377.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08921399B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-3a73931af6cf4683ac17080d17418399 |
| Source note | uspto-grants-2014_12 |