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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1409871Generated: November 1, 2026

2-(3-Methyl-1,2-oxazol-5-yl)acetic acid → HCID 178425861, compound

https://huagongshe.com/reaction/1409871

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Methyl-1,2-oxazol-5-yl)acetic acidHCID 4195532—
ReactantHCID 178478713HCID 178478713—
ProductHCID 178425861HCID 178425861—

Reaction Steps

The title compound, off-white solid (84 mg, 74%), MS (ISP) m/z=450.3 [(M+H)+], mp 165° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and 2-(3-methyl-isoxazol-5-yl)-acetic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921397B2
Source datasetuspto-grants-2014_12
ORD IDord-dff48519773e44a696152d370512cf55
Source noteuspto-grants-2014_12