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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1409873Generated: October 31, 2026

3,3,3-Trifluoropropionic acid → HCID 178520716, compound

https://huagongshe.com/reaction/1409873

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,3,3-Trifluoropropionic acidHCID 2777972—
ReactantHCID 178478713HCID 178478713—
ProductHCID 178520716HCID 178520716—

Reaction Steps

The title compound, off-white solid (84 mg, 77%), MS (ISP) m/z=437.3 [(M+H)+], mp 182° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and 3,3,3-trifluoro-propionic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921397B2
Source datasetuspto-grants-2014_12
ORD IDord-9bba97b5a3944f6d96096c4637eba64a
Source noteuspto-grants-2014_12