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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1409877Generated: November 1, 2026

Propanamide, 2-hydroxy-2-methyl- → HCID 178459878, compound

https://huagongshe.com/reaction/1409877

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropanamide, 2-hydroxy-2-methyl-HCID 83059—
ReactantHCID 178478713HCID 178478713—
ProductHCID 178459878HCID 178459878—

Reaction Steps

The title compound, white solid (65 mg, 63%), MS (ISP) m/z=413.4 [(M+H)+], mp 169° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and 2-hydroxy-2-methyl-propionamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921397B2
Source datasetuspto-grants-2014_12
ORD IDord-de38e608e9904bfe8077911a0f01b272
Source noteuspto-grants-2014_12