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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1409878Generated: November 2, 2026

(R)-Tetrahydro-3-furoic acid → HCID 178523657, compound

https://huagongshe.com/reaction/1409878

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-Tetrahydro-3-furoic acidHCID 4661317—
ReactantHCID 178478713HCID 178478713—
ProductHCID 178523657HCID 178523657—

Reaction Steps

The title compound, light yellow solid (79 mg, 75%), MS (ISP) m/z=425.2 [(M+H)+], mp 183° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and (RS)-tetrahydro-furan-3-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921397B2
Source datasetuspto-grants-2014_12
ORD IDord-2ed5cdb4637c4c39bc739eb2f0b1494a
Source noteuspto-grants-2014_12