Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1409883Generated: October 30, 2026

1-Hydroxy-1-cyclopropanecarboxylic acid → HCID 178523660, compound

https://huagongshe.com/reaction/1409883

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Hydroxy-1-cyclopropanecarboxylic acidHCID 2733160—
ReactantHCID 178478713HCID 178478713—
ProductHCID 178523660HCID 178523660—

Reaction Steps

The title compound, white solid (67 mg, 65%), MS (ISP) m/z=411.3 [(M+H)+], mp 200° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and 1-hydroxy-cyclopropanecarboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921397B2
Source datasetuspto-grants-2014_12
ORD IDord-676b59f2efbd42369d1b2fe1c3f41ec4
Source noteuspto-grants-2014_12