4-Fluorobenzoic Acid → HCID 178523647, compound

Participants

Reaction Steps

The title compound, light yellow solid (92 mg, 82%), MS (ISP) m/z=449.3 [(M+H)+], mp 193° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and 4-fluoro-benzoic acid.

Provenance & Evidence