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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1409889Generated: October 31, 2026

Pivalic acid → HCID 178447383, compound

https://huagongshe.com/reaction/1409889

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPivalic acidHCID 6417—
ReactantHCID 178478713HCID 178478713—
ProductHCID 178447383HCID 178447383—

Reaction Steps

The title compound, white solid (76 mg, 74%), MS (ISP) m/z=411.5 [(M+H)+], mp 157° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and 2,2-dimethyl-propionic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921397B2
Source datasetuspto-grants-2014_12
ORD IDord-b066311c985044a89bddca34944fde93
Source noteuspto-grants-2014_12