HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Oxolan-2-yl)acetic acid → HCID 178520299, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Oxolan-2-yl)acetic acid | HCID 228726 | — |
| Reactant | HCID 178478713 | HCID 178478713 | — |
| Product | HCID 178520299 | HCID 178520299 | — |
Reaction Steps
The title compound, off-white solid (62 mg, 56%), MS (ISP) m/z=439.4 [(M+H)+], mp 149° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and rac-(tetrahydro-furan-2-yl)-acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08921397B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-026c3b7787a04ea79ec6dd2d809996ff |
| Source note | uspto-grants-2014_12 |